Tecnología de información y ventaja competitiva : el caso de los sistemas ERP en Chile

Este trabajo presenta un examen de los factores que anteceden la integración exitosa de una tecnología de información, como son los sistemas ERP (Enterprise Resources Planning), y cuales de estos factores pueden generar una ventaja competitiva sostenible para la empresa. El análisis se basa en un estudio empírico que indagó el fenómeno de implantación exitosa de sistemas ERP en 72 grandes empresas chilenas y lo contrastó con un modelo de investigación propuesto por los autores, utilizando para estos efectos la técnica PLS (Partial Least Square) de modelado de ecuaciones estructurales. Basados en el enfoque conceptual de la teoría de recursos y capacidades, los resultados de la investigación indican que el aprendizaje y la predisposición para el cambio (en conjunción con los otros factores antecedentes del éxito de un sistema ERP y del propio ERP) pueden ser fuentes de una ventaja competitiva sostenible.This paper presents an examination of the factors of successful integration of information technology, such as ERP (Enterprise Resources Planning), and which of these factors can generate a sustainable competitive advantage for the company. The analysis was based on an empirical study that researched the phenomenon of successful implementation of ERP systems in 72 large companies in Chile and contrasted it with a model proposed by the authors, using the technique of structural equation modeling PLS (Partial Least Square). Based on the conceptual approach of resource-based view, research findings indicate that learning and readiness for change (in conjunction with other factors to the success of an ERP system and his own ERP) can be sources a sustainable competitive advantage

Tecnología de información y ventaja competitiva: el caso de los sistemas ERP en Chile

This paper presents an examination of the factors of successful integration of information technology, such as ERP (Enterprise Resources Planning), and which of these factors can generate a sustainable competitive advantage for the company. The analysis was based on an empirical study that researched the phenomenon of successful implementation of ERP systems in 72 large companies in Chile and contrasted it with a model proposed by the authors, using the technique of structural equation modeling PLS (Partial Least Square). Based on the conceptual approach of resource-based view, research findings indicate that learning and readiness for change (in conjunction with other factors to the success of an ERP system and his own ERP) can be sources a sustainable competitive advantage.Este trabajo presenta un examen de los factores que anteceden la integración exitosa de una tecnología de información, como son los sistemas ERP (Enterprise Resources Planning), y cuales de estos factores pueden generar una ventaja competitiva sostenible para la empresa. El análisis se basa en un estudio empírico que indagó el fenómeno de implantación exitosa de sistemas ERP en 72 grandes empresas chilenas y lo contrastó con un modelo de investigación propuesto por los autores, utilizando para estos efectos la técnica PLS (Partial Least Square) de modelado de ecuaciones estructurales. Basados en el enfoque conceptual de la teoría de recursos y capacidades, los resultados de la investigación indican que el aprendizaje y la predisposición para el cambio (en conjunción con los otros factores antecedentes del éxito de un sistema ERP y del propio ERP) pueden ser fuentes de una ventaja competitiva sostenible

Thermal convection in fluidized granular systems

Thermal convection is observed in molecular dynamic simulation of a fluidized granular system of nearly elastic hard disks moving under gravity, inside a rectangular box. Boundaries introduce no shearing or time dependence, but the energy injection comes from a slip (shear-free) thermalizing base. The top wall is perfectly elastic and lateral boundaries are either elastic or periodic. The observed convection comes from the effect of gravity and the spontaneous granular temperature gradient that the system dynamically develops.Comment: 4 pages, 5 figure

Hydrodynamic theory for granular gases

A granular gas subjected to a permanent injection of energy is described by means of hydrodynamic equations derived from a moment expansion method. The method uses as reference function not a Maxwellian distribution $f_{\sf M}$ but a distribution $f_0 = \Phi f_{\sf M}$, such that $\Phi$ adds a fourth cumulant $\kappa$ to the velocity distribution. The formalism is applied to a stationary conductive case showing that the theory fits extraordinarily well the results coming from our molecular dynamic simulations once we determine $\kappa$ as a function of the inelasticity of the particle-particle collisions. The shape of $\kappa$ is independent of the size $N$ of the system.Comment: 10 pages, 9 figures, more about our research in http://www.cec.uchile.cl/cinetica

Clinical trial to assess the effect of physical exercise on endothelial function and insulin resistance in pregnant women

<p>Abstract</p> <p>Background</p> <p>Preeclampsia (PE) is a common maternal disease that complicates 5 to 10% of pregnancies and remains as the major cause of maternal and neonatal mortality. Cost-effective interventions aimed at preventing the development of preeclampsia are urgently needed. However, the pathogenesis of PE is not well known. Multiple mechanisms such as oxidative stress, endothelial dysfunction and insulin resistance may contribute to its development. Regular aerobic exercise recovers endothelial function; improves insulin resistance and decreases oxidative stress. Therefore the purpose of this clinical trial is to determine the effect of regular aerobic exercise on endothelial function, on insulin resistance and on pregnancy outcome.</p> <p>Methods and design</p> <p>64 pregnant women will be included in a blind, randomized clinical trial, and parallel assignment. The exercise group will do regular aerobic physical exercise: walking (10 minutes), aerobic exercise (30 minutes), stretching (10 minutes) and relaxation exercise (10 minutes) in three sessions per week. Control group will do the activities of daily living (bathing, dressing, eating, and walking) without counselling from a physical therapist.</p> <p>Trial registration</p> <p>NCT00741312.</p

Eligibility criteria for Menopausal Hormone Therapy (MHT): a position statement from a consortium of scientific societies for the use of MHT in women with medical conditions. MHT Eligibility Criteria Group

This project aims to develop eligibility criteria for menopausal hormone therapy (MHT). The tool should be similar to those already established for contraception A consortium of scientific societies coordinated by the Spanish Menopause Society met to formulate recommendations for the use of MHT by women with medical conditions based on the best available evidence. The project was developed in two phases. As a first step, we conducted 14 systematic reviews and 32 metanalyses on the safety of MHT (in nine areas: age, time of menopause onset, treatment duration, women with thrombotic risk, women with a personal history of cardiovascular disease, women with metabolic syndrome, women with gastrointestinal diseases, survivors of breast cancer or of other cancers, and women who smoke) and on the most relevant pharmacological interactions with MHT. These systematic reviews and metanalyses helped inform a structured process in which a panel of experts defined the eligibility criteria according to a specific framework, which facilitated the discussion and development process. To unify the proposal, the following eligibility criteria have been defined in accordance with the WHO international nomenclature for the different alternatives for MHT (category 1, no restriction on the use of MHT; category 2, the benefits outweigh the risks; category 3, the risks generally outweigh the benefits; category 4, MHT should not be used). Quality was classified as high, moderate, low or very low, based on several factors (including risk of bias, inaccuracy, inconsistency, lack of directionality and publication bias). When no direct evidence was identified, but plausibility, clinical experience or indirect evidence were available, "Expert opinion" was categorized. For the first time, a set of eligibility criteria, based on clinical evidence and developed according to the most rigorous methodological tools, has been defined. This will provide health professionals with a powerful decision-making tool that can be used to manage menopausal symptoms

A global agenda for advancing freshwater biodiversity research

This manuscript is a contribution of the Alliance for Freshwater Life (www.allianceforfreshwaterlife.org). We thank Nick Bond, Lisa Bossenbroek, Lekima Copeland, Dean Jacobsen, Maria Cecilia Londo?o, David Lopez, Jaime Ricardo Garcia Marquez, Ketlhatlogile Mosepele, Nunia Thomas-Moko, Qiwei Wei and the authors of Living Waters: A Research Agenda for the Biodiversity of Inland and Coastal Waters for their contributions. We also thank Peter Thrall, Ian Harrison and two anonymous referees for their valuable comments that helped improve the manuscript. Open access funding enabled and organised by Projekt DEAL

A global agenda for advancing freshwater biodiversity research

Global freshwater biodiversity is declining dramatically, and meeting the challenges of this crisis requires bold goals and the mobilisation of substantial resources. While the reasons are varied, investments in both research and conservation of freshwater biodiversity lag far behind those in the terrestrial and marine realms. Inspired by a global consultation, we identify 15 pressing priority needs, grouped into five research areas, in an effort to support informed stewardship of freshwater biodiversity. The proposed agenda aims to advance freshwater biodiversity research globally as a critical step in improving coordinated actions towards its sustainable management and conservation.Peer reviewe

Update of the PANCCO clinical practice guidelines for the treatment of ulcerative colitis in the adult population

Ulcerative colitis (US) is a chronic disease of unknown etiology. It is incurable and its clinical course is intermittent, characterized by periods of remission and relapse. The prevalence and incidence of the disease has been increasing worldwide. The update presented herein includes the participation of healthcare professionals, decision-makers, and a representative of the patients, all of whom declared their conflicts of interest. Answerable clinical questions were formulated, and the outcomes were graded. The information search was conducted on the Medline/PubMed, Embase, Epistemonikos, and LILACS databases, and covered grey literature sources, as well. The search was updated on November 30, 2020, with no restrictions regarding date or language. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) classification system was implemented to establish the strength of the recommendation and quality of evidence. A formal consensus was developed, based on the RAND/UCLA methodology and the document was peer reviewed. The short version of the Clinical Practice Guidelines for the Treatment of Ulcerative Colitis in the Adult Population is presented herein, together with the supporting evidence and respective recommendations. In mild-to-moderate UC, budesonide MMX is an option when treatment with 5-ASA fails, and before using systemic steroids. In moderate-to-severe UC, infliximab, adalimumab, vedolizumab, ustekinumab, and tofacitinib can be used as first-line therapy. If there is anti-TNF therapy failure, ustekinumab and tofacitinib provide the best results. In patients with antibiotic-refractory pouchitis, anti-TNFs are the treatment of choice